BDBM262123 6-Amino-9-[(4-fluorophenyl)methyl]-2-(propylsulfonimidoyl)-7H-purin-8-one::US11242345, Example 24::US9708325, 24

SMILES CCCS(=N)(=O)c1nc(N)c2[nH]c(=O)n(Cc3ccc(F)cc3)c2n1

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 262123   

TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM262123(6-Amino-9-[(4-fluorophenyl)methyl]-2-(propylsulfon...)
Affinity DataEC50:  37nMAssay Description:A stable HEK-Blue-hTLR7 cell line was purchased from InvivoGen (Cat. #: hkb-htlr7, San Diego, Calif., USA). These cells were designed for studying th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetToll-like receptor 7(Homo sapiens (Human))
Hoffmann-La Roche

US Patent
LigandPNGBDBM262123(6-Amino-9-[(4-fluorophenyl)methyl]-2-(propylsulfon...)
Affinity DataEC50:  37nMAssay Description:HEK-Blue-hTLR7 cells were incubated at a density of 250,000˜450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Mod...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent