BDBM262612 4-((4-fluoropiperidin-4-yl)methyl)-4′-(piperidin-4-yl)- 2-(2H-tetrazol-5-yl)-[1,1′-biphenyl]-3-sulfonamide::US9708336, 464

SMILES NS(=O)(=O)c1c(CC2(F)CCNCC2)ccc(-c2ccc(cc2)C2CCNCC2)c1-c1nn[nH]n1

InChI Key InChIKey=GRGWHWUIYWRYID-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262612   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262612(4-((4-fluoropiperidin-4-yl)methyl)-4′-(piper...)
Affinity DataIC50:  18.7nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262612(4-((4-fluoropiperidin-4-yl)methyl)-4′-(piper...)
Affinity DataIC50:  1.95nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262612(4-((4-fluoropiperidin-4-yl)methyl)-4′-(piper...)
Affinity DataIC50:  3.82nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent