BDBM262622 3-(1H-pyrrolo[3,2-b]pyridin-6-yl)-2- (1H-tetrazol-5-yl)-6- (trifluoromethyl)benzenesulfonamide::US9708336, 474

SMILES NS(=O)(=O)c1c(ccc(-c2cnc3cc[nH]c3c2)c1-c1nnn[nH]1)C(F)(F)F

InChI Key InChIKey=TVFBTLXEPYKCBH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262622   

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262622(3-(1H-pyrrolo[3,2-b]pyridin-6-yl)-2- (1H-tetrazol-...)
Affinity DataIC50:  3.91nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVIM-1 metallo-beta-lactamase(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262622(3-(1H-pyrrolo[3,2-b]pyridin-6-yl)-2- (1H-tetrazol-...)
Affinity DataIC50:  0.549nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM262622(3-(1H-pyrrolo[3,2-b]pyridin-6-yl)-2- (1H-tetrazol-...)
Affinity DataIC50:  0.523nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent