BDBM263346 US9546162, 4

SMILES OC(=O)c1ccc(CCc2cccc3CCN(Cc4cc(cc(c4)C(F)(F)F)C(F)(F)F)c23)cc1

InChI Key InChIKey=NXOQDGHYBZYSSC-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 263346   

TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM263346(US9546162, 4)
Affinity DataKi:  0.300nM EC50:  11nMpH: 7.4Assay Description:Cells were seeded at a density of 5×104 cells per well in Biocoat® Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM263346(US9546162, 4)
Affinity DataKi:  52nM EC50:  71nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM263346(US9546162, 4)
Affinity DataKi:  61nMpH: 7.4Assay Description:HEK-293 cells stably expressing the human or feline FP receptor, or EP1, EP2, or EP4 receptors were washed with TME buffer, scraped from the bottom o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM263346(US9546162, 4)
Affinity DataKi:  1.20E+3nMpH: 7.4Assay Description:Cells were seeded at a density of 5×104 cells per well in Biocoat® Poly-D-lysine-coated black-wall, clear-bottom 96-well plates (Becton-Dickinson) an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent