BDBM263491 (s)-2-(7-methoxy-4-oxobenzo[d][1,2,3]triazin-3(4h)-yl)-n-(1-(4-(trifluoromethyl)phenyl)ethyl)acetamide::US10561662, Example 59::US11173161, EX 59::US9556130, test 59
SMILES COc1ccc2c(c1)nnn(CC(=O)N[C@@H](C)c1ccc(cc1)C(F)(F)F)c2=O
InChI Key InChIKey=GMJKPWYOVYYMIA-NSHDSACASA-N
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 263491
Affinity DataKi: 375nM ΔG°: -8.14kcal/molepH: 7.4 T: 2°CAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair
Affinity DataKi: 375nMAssay Description:Membranes were removed from −80° C., thawed and diluted in cold radioligand assay buffer (20 mM HEPES pH 7.4/5 mM MgCl2/1 mM CaCl2/Roche protea...More data for this Ligand-Target Pair
Affinity DataKi: 3.75E+5nMAssay Description:This membrane based assay measures the ability of compounds to competitively bind GPR139 in stably transfected CHO-TRex membranes. CHO-TRex (Life Tec...More data for this Ligand-Target Pair