BDBM263552 2-{5-amino-1-[4-(3-cyano- phenoxy)-2-methyl-phenyl]-1h- pyrazole-4-carbonyl}-1h- benzoimidazole-5-carboxylic acid (2-methoxy-ethyl)-amide::US9556150, i-40

SMILES COCCNC(=O)c1ccc2[nH]c(nc2c1)C(=O)c1cnn(c1N)-c1ccc(Oc2cccc(c2)C#N)cc1C

InChI Key InChIKey=IODXVWPVLGPERS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263552   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
F. Hoffmann-La Roche

US Patent
LigandPNGBDBM263552(2-{5-amino-1-[4-(3-cyano- phenoxy)-2-methyl-phenyl...)
Affinity DataIC50:  23nMpH: 7.15Assay Description:This BTK competition assay measures compound potency (IC50) for the inactivated state of Bruton's Tyrosine Kinase using FRET (Förster/Fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent