BDBM263619 2-(tert-butyl)-4-chloro-5-((4-(4-(fluoromethyl)phenyl)but-3-yn-1-yl)oxy)pyridazin-3(2H)-one::US9713651, 49

SMILES CC(C)(C)n1ncc(OCCC#Cc2ccc(CF)cc2)c(Cl)c1=O

InChI Key InChIKey=JNHLQLPXGMGFAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263619   

TargetNADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial(Bos taurus)
Lantheus Medical Imaging

US Patent
LigandPNGBDBM263619(2-(tert-butyl)-4-chloro-5-((4-(4-(fluoromethyl)phe...)
Affinity DataIC50: >1.00E+3nMpH: 7.4Assay Description:The procedure for determining catalytic activity of submitochondrial particles was adapted from Satoh et al. (e.g., see Satoh T, Miyoshi H, Sakamoto ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent