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BDBM263628 2-(tert-butyl)-4-chloro-5-((4-((2-fluoropropoxy)ethoxy)methyl)benzyl)oxy)pyridazin-3 (2H)-one::US9713651, 17

SMILES: CC(C)(C)n1ncc(OCc2ccc(COCCOCCCF)cc2)c(Cl)c1=O

InChI Key: InChIKey=WCDVGPSUCFFHED-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 263628   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial


(Bos taurus)
BDBM263628
PNG
(2-(tert-butyl)-4-chloro-5-((4-((2-fluoropropoxy)et...)
Show SMILES CC(C)(C)n1ncc(OCc2ccc(COCCOCCCF)cc2)c(Cl)c1=O
Show InChI InChI=1S/C21H28ClFN2O4/c1-21(2,3)25-20(26)19(22)18(13-24-25)29-15-17-7-5-16(6-8-17)14-28-12-11-27-10-4-9-23/h5-8,13H,4,9-12,14-15H2,1-3H3
PDB

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KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<1.00E+3n/an/an/an/a7.4n/a



Lantheus Medical Imaging, Inc.

US Patent


Assay Description
The procedure for determining catalytic activity of submitochondrial particles was adapted from Satoh et al. (e.g., see Satoh T, Miyoshi H, Sakamoto ...


US Patent US9713651 (2017)

More data for this
Ligand-Target Pair