BDBM264004 2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyridine-4-carboxylic acid::US10173996, Example 82::US9604961, Example 82::US9714230, 82::US9908865, Example 82

SMILES CC(Oc1ccnn1-c1cc(ccn1)C(O)=O)c1ccc(F)cc1

InChI Key InChIKey=OEHJHVSOQQJIGN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 264004   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264004(2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyri...)
Affinity DataIC50: <100nMAssay Description:The enzymatic assay of Jarid1A activity is based upon Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The ability of test c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264004(2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyri...)
Affinity DataIC50: <100nMAssay Description:The ability of test compounds to inhibit the activity of Jarid1B was determined in 384-well plate format under the following reaction conditions: 0.8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific demethylase 5B(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264004(2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyri...)
Affinity DataIC50:  41nMAssay Description:Inhibition of KDM5B (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264004(2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyri...)
Affinity DataIC50:  310nMAssay Description:Inhibition of KDM4C (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM264004(2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyri...)
Affinity DataIC50:  180nMAssay Description:Inhibition of KDM5A (unknown origin) preincubated with enzymeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Celgene

Curated by ChEMBL
LigandPNGBDBM264004(2-[5-[1-(4- fluorophenyl)ethoxy]pyrazol-1- yl]pyri...)
Affinity DataIC50:  550nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent