BDBM264097 1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin-1-yl)phenyl)pyridin-2(1H)-one::US9714232, 10

SMILES Fc1ccc2[nH]cc(CCCCN3CCN(CC3)c3ccc(cc3)-n3ccccc3=O)c2c1

InChI Key InChIKey=QYBYQUFQYMHNIV-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264097   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264097(1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataKi:  0.190nMpH: 7.4Assay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-0H-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM264097(1-(4-(4-(4-(5-fluoro-1H-indol-3-yl)butyl)piperazin...)
Affinity DataIC50:  1.60nMpH: 7.4Assay Description:The synaptosomes (150 μg) prepared from a rat brain were incubated at 37° C. for 15 minutes with 0.1 μCi [3H]5-HT in the absence or presenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent