BDBM264169 (E)-N-(7-(((R)-1,4-dioxan-2-yl)methoxy)-4-(3-chloro-4-fluorophenylamino)quinazolin-6-yl)-4-(2-(hydroxymethyl)azetidin-1-yl)but-2-enamide::US9714235, 13
SMILES OCC1CCN1C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC[C@H]1COCCO1
InChI Key InChIKey=QJNMNCUMDUMIJV-CBCWIBMJSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 264169
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Shanghai Fochon Pharmaceutical
US Patent
Shanghai Fochon Pharmaceutical
US Patent
Affinity DataIC50: 13.5nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:To investigate whether a compound is able to inhibit the activity of EGFR and ErbB2 in cells, a mechanism-based assay using BT474 (EGFR overexpressio...More data for this Ligand-Target Pair