BDBM264259 6-(2,6-Dichlorophenyl)-2-((3-methoxy-4-(piperazin-1-yl)phenyl)amino)pyrido[4,3-d]pyrimidin-5(6H)-one, HCl::US9714244, 13

SMILES COc1cc(Nc2ncc3c(ccn(-c4c(Cl)cccc4Cl)c3=O)n2)ccc1N1CCNCC1

InChI Key InChIKey=POKMRPKLRXBNFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264259   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Almac Discovery

US Patent
LigandPNGBDBM264259(6-(2,6-Dichlorophenyl)-2-((3-methoxy-4-(piperazin-...)
Affinity DataIC50: <10nMAssay Description:Compounds were tested for inhibition of the human ether a go-go related gene (hERG) K+ channel using IonWorks patch clamp electrophysiology at Essen ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetWee1-like protein kinase(Homo sapiens (Human))
Almac Discovery

US Patent
LigandPNGBDBM264259(6-(2,6-Dichlorophenyl)-2-((3-methoxy-4-(piperazin-...)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:In the measurement of Wee-1 activity, a commercial peptide Poly(Lys Tyr(4:1)) hydrobromide was purchased from Sigma Aldrich and used as the substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent