BDBM264428 US9714247, 150

SMILES CN1CC[C@@H](C1)n1c2cc(Nc3ccc(F)cn3)ncc2cc(-c2c(F)cccc2F)c1=O

InChI Key InChIKey=NCWNVZMHTRKEOP-INIZCTEOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264428   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264428(US9714247, 150)
Affinity DataIC50: <100nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264428(US9714247, 150)
Affinity DataIC50:  550nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Tolero Pharmaceuticals

US Patent
LigandPNGBDBM264428(US9714247, 150)
Affinity DataIC50:  550nMAssay Description:A concentration of a drug that reduces the observed activity of an enzyme by 50%. An IC50 is not a true affinity constant and the specific value dete...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent