BDBM264517 17-(pyrimidin-5-yl)-N-(2-sulphamoylethyl)oestra-1,3,5(10),16-tetraene-3-carboxamide::US9714266, 47

SMILES C[C@]12CC[C@H]3[C@@H](CCc4cc(ccc34)C(=O)NCCS(N)(=O)=O)[C@@H]1CC=C2c1cncnc1

InChI Key InChIKey=FCIRGZUGDBOUQR-NTNMUZRVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 264517   

TargetAldo-keto reductase family 1 member C3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM264517(17-(pyrimidin-5-yl)-N-(2-sulphamoylethyl)oestra-1,...)
Affinity DataIC50:  119nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent