BDBM264610 US9718760, C165

SMILES Oc1ccc(cc1O)S(=O)(=O)N(c1ccc(cc1)-c1ccccc1)S(=O)(=O)c1ccc(O)c(O)c1

InChI Key InChIKey=XPHZPHGXWCMXJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264610   

TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM264610(US9718760, C165)
Affinity DataIC50:  510nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasminogen activator inhibitor 1/Urokinase-type plasminogen activator(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM264610(US9718760, C165)
Affinity DataIC50:  350nMpH: 7.4 T: 2°CAssay Description:To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent