BDBM264627 US9718760, C160

SMILES Oc1ccc(cc1O)S(=O)(=O)NCc1ccccc1

InChI Key InChIKey=PWUHSENCXPKXKJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 264627   

TargetPlasminogen activator inhibitor 1/Urokinase-type plasminogen activator(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM264627(US9718760, C160)
Affinity DataIC50:  3.90E+4nMpH: 7.4 T: 2°CAssay Description:To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAntithrombin-III/Prothrombin(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM264627(US9718760, C160)
Affinity DataIC50:  2.33E+6nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlasminogen activator inhibitor 1/Tissue-type plasminogen activator(Homo sapiens (Human))
University Of Michigan

US Patent
LigandPNGBDBM264627(US9718760, C160)
Affinity DataIC50:  5.82E+4nMT: 2°CAssay Description:PAI-1 inhibitor compounds were dissolved in DMSO to a final concentration of (10-50 mM), depending upon solubility. Compounds were then diluted in ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent