BDBM265185 US10413550, Example 41a::US11234987, Example 41a::US9718793, 41a

SMILES CCNC(=O)c1noc(c1-c1ccc(CNCc2ccoc2)cc1)-c1cc(Cl)c(O)cc1O

InChI Key InChIKey=VVUMWFROLMIEAH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 265185   

TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM265185(US10413550, Example 41a | US11234987, Example 41a ...)
Affinity DataIC50: <1.00E+4nMAssay Description:Fluorescence polarization {also known as fluorescence anisotropy} measures the rotation of a fluorescing species in solution, where the larger molecu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATP-dependent molecular chaperone HSP82(Saccharomyces cerevisiae)
Cancer Research Technology

US Patent
LigandPNGBDBM265185(US10413550, Example 41a | US11234987, Example 41a ...)
Affinity DataIC50: <1.00E+4nMAssay Description:1) Costar 96-well black assay plate. Assay buffer of (a) 100 mM Tris pH7.4; (b) 20 mM KCl; (c) 6 mM MgCl2. Stored at room temperature.3) BSA (bovine ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEndoplasmin/Heat shock protein 75/Heat shock protein HSP 90-alpha/Heat shock protein HSP 90-beta(Homo sapiens (Human))
The Institute Of Cancer Research

US Patent
LigandPNGBDBM265185(US10413550, Example 41a | US11234987, Example 41a ...)
Affinity DataIC50: <1.00E+4nMAssay Description: (1) Greiner 384-well (Greiner 781101) or Costar 384-well flat-bottomed polystyrene multiwell plates (VWR). (2) Assay buffer of (a) 100 mM Tris...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent