BDBM26578 3-({5-[(2-carboxyethyl)sulfanyl]-1,3,4-thiadiazol-2-yl}sulfanyl)propanoic acid::A1NI2, 3

SMILES OC(=O)CCSc1nnc(SCCC(O)=O)s1

InChI Key InChIKey=NQNRYGGKRLWMRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26578   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University Of Southern California

LigandPNGBDBM26578(3-({5-[(2-carboxyethyl)sulfanyl]-1,3,4-thiadiazol-...)
Affinity DataIC50:  1.70E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed