BDBM26630 (5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidine-2,4-dione::thiazolidine-2,4-dione, 8a

SMILES CCc1ccc(C=C2SC(O)=NC2=O)cc1

InChI Key InChIKey=DZPOUCQZRNTFFR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 26630   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Medical University Of South Carolina

LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  600nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of IGF1R by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInsulin receptor(Homo sapiens (Human))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of IR by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Medical University Of South Carolina

LigandPNGBDBM26630((5Z)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  300nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed