BDBM26659 7,3-dihydroxyflavone::7-hydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one

SMILES Oc1cccc(c1)-c1cc(=O)c2ccc(O)cc2o1

InChI Key InChIKey=DYARIVMCYYQNNQ-UHFFFAOYSA-N

Data  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26659   

TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University

LigandPNGBDBM26659(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
Affinity DataIC50:  4.52E+3nMpH: 7.0 T: 30°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Loma Linda University

LigandPNGBDBM26659(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
Affinity DataIC50:  4.57E+3nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM26659(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
Affinity DataIC50:  280nMAssay Description:Inhibition of human 6XHis-tagged TNKS1 SAM-ART domain (1030 to 1317 amino acid residues) by fluorescence assayMore data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM26659(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human recombinant ARTD1 by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Human)
University of Oulu

Curated by ChEMBL
LigandPNGBDBM26659(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
Affinity DataIC50:  620nMAssay Description:Inhibition of human 6XHis-tagged TNKS2 ART domain (946 to 1161 amino acid residues) expressed in Escherichia coli Rosetta2 (DE3) by fluorescence assa...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM26659(7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxypheny...)
Affinity DataIC50:  3.93E+4nMAssay Description:Inhibition of p56 lckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed