BDBM26661 7,3,4,5-tetrahydroxyflavone::7-hydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chromen-4-one

SMILES Oc1ccc2c(c1)oc(cc2=O)-c1cc(O)c(O)c(O)c1

InChI Key InChIKey=CCCIGFPBADVTFE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26661   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26661(7,3,4,5-tetrahydroxyflavone | 7-hydroxy-2-(3,4,5-t...)
Affinity DataIC50:  7.80E+3nMpH: 7.0 T: 2°CAssay Description:The 96-well flat-bottomed plates were coated with recombinant GST-BAD. After the plates were blocked, the reaction buffer containing test compound an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase S(Homo sapiens (Human))
Chungnam National University

Curated by ChEMBL
LigandPNGBDBM26661(7,3,4,5-tetrahydroxyflavone | 7-hydroxy-2-(3,4,5-t...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of recombinant human PTP-sigma (residues 1367 to 1948) using para-nitrophenylphosphate as substrate for 60 mins by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Loma Linda University

LigandPNGBDBM26661(7,3,4,5-tetrahydroxyflavone | 7-hydroxy-2-(3,4,5-t...)
Affinity DataIC50:  7.76E+3nMAssay Description:Inhibition of PIM1 kinaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed