BDBM26674 6-(2-hydroxy-5-methylphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile::pyridone-based compound, 2

SMILES Cc1ccc(O)c(c1)-c1cc(-c2ccccc2)c(C#N)c(=O)[nH]1

InChI Key InChIKey=IALVZRHASRCEQM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26674   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26674(6-(2-hydroxy-5-methylphenyl)-2-oxo-4-phenyl-1,2-di...)
Affinity DataIC50:  340nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed