BDBM26677 4-(3-chlorophenyl)-6-(5-ethyl-2-hydroxyphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile::pyridone-based compound, 5

SMILES CCc1ccc(O)c(c1)-c1cc(-c2cccc(Cl)c2)c(C#N)c(=O)[nH]1

InChI Key InChIKey=MVKIENHABBALPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26677   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Valeant Pharmaceuticals Research And Development

LigandPNGBDBM26677(4-(3-chlorophenyl)-6-(5-ethyl-2-hydroxyphenyl)-2-o...)
Affinity DataIC50:  1.03E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed