BindingDB logo
myBDB logout

BDBM267062 Butyl 4-{[(4,5-dichloro-2-thienyl)sulfonyl]amino}-2-hydroxybenzoate::US9718809, 70

SMILES: CCCCOC(=O)c1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)cc1O

InChI Key: InChIKey=WOLMPRVUNHSAGP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267062   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4)


(Homo sapiens (Human))
BDBM267062
PNG
(Butyl 4-{[(4,5-dichloro-2-thienyl)sulfonyl]amino}-...)
Show SMILES CCCCOC(=O)c1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)cc1O
Show InChI InChI=1S/C15H15Cl2NO5S2/c1-2-3-6-23-15(20)10-5-4-9(7-12(10)19)18-25(21,22)13-8-11(16)14(17)24-13/h4-5,7-8,18-19H,2-3,6H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 200n/an/an/an/an/an/a



Kancera AB

US Patent


Assay Description
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...


US Patent US9718809 (2017)

More data for this
Ligand-Target Pair