BDBM267254 3-chloro-5-((6-oxo-1- ((6-oxo-5-(p-tolyl)- 1,6-dihydropyridazin- 3-yl)methyl)-4- (trifluoromethyl)-1,6- dihydropyrimidin-5- yl)oxy)benzonitrile::US10189831, Example 31::US9718819, 31

SMILES Cc1ccc(cc1)-c1cc(Cn2cnc(c(Oc3cc(Cl)cc(c3)C#N)c2=O)C(F)(F)F)n[nH]c1=O

InChI Key InChIKey=HRGAUANJPVMUQP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267254   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267254(3-chloro-5-((6-oxo-1- ((6-oxo-5-(p-tolyl)- 1,6-dih...)
Affinity DataIC50:  5nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267254(3-chloro-5-((6-oxo-1- ((6-oxo-5-(p-tolyl)- 1,6-dih...)
Affinity DataIC50:  5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent