BDBM267289 3-chloro-5-((1-((5- cyclopropyl-6-oxo- 1,6-dihydropyridazin- 3-yl)methyl)-6-oxo- 4-(trifluoromethyl)- 1,6- dihydropyrimidin-5- yl)oxy)benzonitrile::US10189831, Example 66::US9718819, 66
SMILES FC(F)(F)c1ncn(Cc2cc(C3CC3)c(=O)[nH]n2)c(=O)c1Oc1cc(Cl)cc(c1)C#N
InChI Key InChIKey=XPVMGHIKFWHSSX-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 267289
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 7nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 7nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair