BDBM267309 3-chloro-5-((1-((5-(6- chloropyridin-3-yl)-6- oxo-1,6- dihydropyridazin-3- yl)methyl)-6-oxo-4- (trifluoromethyl)-1,6- dihydropyrimidin-5- yl)oxy)benzonitrile::US10189831, Example 86::US9718819, 86
SMILES FC(F)(F)c1ncn(Cc2cc(-c3ccc(Cl)nc3)c(=O)[nH]n2)c(=O)c1Oc1cc(Cl)cc(c1)C#N
InChI Key InChIKey=HRXQUTFAETXIBJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 267309
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 6nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair