BDBM267309 3-chloro-5-((1-((5-(6- chloropyridin-3-yl)-6- oxo-1,6- dihydropyridazin-3- yl)methyl)-6-oxo-4- (trifluoromethyl)-1,6- dihydropyrimidin-5- yl)oxy)benzonitrile::US10189831, Example 86::US9718819, 86

SMILES FC(F)(F)c1ncn(Cc2cc(-c3ccc(Cl)nc3)c(=O)[nH]n2)c(=O)c1Oc1cc(Cl)cc(c1)C#N

InChI Key InChIKey=HRXQUTFAETXIBJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267309   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267309(3-chloro-5-((1-((5-(6- chloropyridin-3-yl)-6- oxo-...)
Affinity DataIC50:  6nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267309(3-chloro-5-((1-((5-(6- chloropyridin-3-yl)-6- oxo-...)
Affinity DataIC50:  6nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent