BDBM267311 3-chloro-5-((6-oxo-1-((6- oxo-5-(quinolin-3-yl)- 1,6-dihydropyridazin-3- yl)methyl)-4- (trifluoromethyl)-1,6- dihydropyrimidin-5- yl)oxy)benzonitrile::US10189831, Example 88::US9718819, 88
SMILES FC(F)(F)c1ncn(Cc2cc(-c3cnc4ccccc4c3)c(=O)[nH]n2)c(=O)c1Oc1cc(Cl)cc(c1)C#N
InChI Key InChIKey=QENGNGDBTVUSAV-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 267311
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 17nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 17nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair