BDBM267390 3-chloro-5-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-dihydropyridazin- 3-yl)methyl)-4- methyl-6-oxo-1,6- dihydropyrimidin-5- yl)oxy)benzonitrile::US10189831, Example 166::US9718819, 166

SMILES FC(F)Oc1ncn(Cc2cc(-c3ccc(F)cc3)c(=O)[nH]n2)c(=O)c1Oc1cc(Cl)cc(c1)C#N

InChI Key InChIKey=JEVSYGZBOKEQFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267390   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267390(3-chloro-5-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50:  3nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267390(3-chloro-5-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50:  3nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent