BDBM267392 5-fluoro-3-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-dihydropyridazin- 3-yl)methyl)-6-oxo- 4-(trifluoromethyl)- 1,6- dihydropyrimidin-5- yl)oxy)-2- methylbenzonitrile::US10189831, Example 168::US9718819, 168

SMILES Cc1c(Oc2c(ncn(Cc3cc(-c4ccc(F)cc4)c(=O)[nH]n3)c2=O)C(F)(F)F)cc(F)cc1[N+]#[C-]

InChI Key InChIKey=NNAGNYLFGGDCGF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267392   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267392(5-fluoro-3-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50:  5nMAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM267392(5-fluoro-3-((1-((5-(4- fluorophenyl)-6-oxo- 1,6-di...)
Affinity DataIC50:  5nMpH: 7.8 T: 2°CAssay Description:The heterodimeric nucleic acid substrate used in the HIV-1 RT polymerase reactions was generated by annealing the DNA primer, biotinylated pD500 (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent