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BDBM267447 US9718822, 30

SMILES: Fc1cnc2OCCCNC(=O)c3cnn4ccc(nc34)N3[C@H](COC3=O)c2c1

InChI Key: InChIKey=HODOGORARXFPKU-CYBMUJFWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267447   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM267447
PNG
(US9718822, 30)
Show SMILES Fc1cnc2OCCCNC(=O)c3cnn4ccc(nc34)N3[C@H](COC3=O)c2c1
Show InChI InChI=1S/C18H15FN6O4/c19-10-6-11-13-9-29-18(27)25(13)14-2-4-24-15(23-14)12(8-22-24)16(26)20-3-1-5-28-17(11)21-7-10/h2,4,6-8,13H,1,3,5,9H2,(H,20,26)/t13-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/a7.5n/a



Array BioPharma, Inc.

US Patent


Assay Description
An enzyme-linked immunosorbant assay (ELISA) was used to assess TrkA kinase activity in the presence of inhibitors. Immulon 4HBX 384-well microtiter ...


US Patent US9718822 (2017)

More data for this
Ligand-Target Pair