BDBM267464 US9718822, 42-B::US9750744, Example 42-B::US9902741, Example 42-B

SMILES O[C@@H]1C[C@@H]2N(C1)c1ccn3ncc(C(=O)NCCCOc4ccc(F)cc24)c3n1

InChI Key InChIKey=XLASNYKWHJNDIR-CJNGLKHVSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 267464   

TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM267464(US9718822, 42-B | US9750744, Example 42-B | US9902...)
Affinity DataIC50:  1.55E+3nMpH: 7.5Assay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen¿ Eu Kinase Binding Assay. In this assay, His-tagged recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM267464(US9718822, 42-B | US9750744, Example 42-B | US9902...)
Affinity DataIC50:  1.00E+3nMAssay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen™ Eu Kinase Binding Assay. In this assay, His-tagged recombina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Array Biopharma

US Patent
LigandPNGBDBM267464(US9718822, 42-B | US9750744, Example 42-B | US9902...)
Affinity DataIC50:  1.00E+3nMAssay Description:The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen Eu Kinase Binding Assay. In this assay, His-tagged recombinan...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent