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BDBM267465 US9718822, 43

SMILES: O[C@@H]1C[C@H]2N(C1)c1ccn3ncc(C(=O)NCCOc4ccc(F)cc24)c3n1

InChI Key: InChIKey=GAULVBGMKYMLPM-IUODEOHRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267465   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
High affinity nerve growth factor receptor


(Homo Sapiens)
BDBM267465
PNG
(US9718822, 43)
Show SMILES O[C@@H]1C[C@H]2N(C1)c1ccn3ncc(C(=O)NCCOc4ccc(F)cc24)c3n1
Show InChI InChI=1S/C19H18FN5O3/c20-11-1-2-16-13(7-11)15-8-12(26)10-24(15)17-3-5-25-18(23-17)14(9-22-25)19(27)21-4-6-28-16/h1-3,5,7,9,12,15,26H,4,6,8,10H2,(H,21,27)/t12-,15-/m1/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 55n/an/an/an/a7.5n/a



Array BioPharma, Inc.

US Patent


Assay Description
The ability of a compound to bind to TrkA was measured by Invitrogen's LanthaScreen¿ Eu Kinase Binding Assay. In this assay, His-tagged recombina...


US Patent US9718822 (2017)

More data for this
Ligand-Target Pair