BDBM26757 bisarylimidazole derivative, 16::phenyl N-[6-(2-methyl-4,5-diphenyl-1H-imidazol-1-yl)hexyl]carbamate

SMILES Cc1nc(c(-c2ccccc2)n1CCCCCCNC(=O)Oc1ccccc1)-c1ccccc1

InChI Key InChIKey=KCHOVCICRIAYSX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26757   

TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Max Planck Institute Of Molecular Physiology

Curated by ChEMBL
LigandPNGBDBM26757(bisarylimidazole derivative, 16 | phenyl N-[6-(2-m...)
Affinity DataIC50:  340nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome FAAH assessed as reduction in 4-pyren-1-ylbutanoic acid release after 60 mins by reverse phase HPLC-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM26757(bisarylimidazole derivative, 16 | phenyl N-[6-(2-m...)
Affinity DataIC50:  5.30nMpH: 9.0 T: 2°CAssay Description:FAAH Inhibition Assay [3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed