BDBM26806 (3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]methyl}benzene)oxane-3,4-diamido::CHEMBL253275::benzimidazole analog., 32
SMILES ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cn2c(nc3ccccc23)C(F)(F)F)cc1
InChI Key InChIKey=PGVYYPZKXKGBLD-JKSUJKDBSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 26806
TargetA disintegrin and metalloproteinase with thrombospondin motifs 1(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of ADAMTS1More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 1.90E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: 6.70E+3nMAssay Description:Inhibition of ADAMTS4More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
University Of Athens
Curated by ChEMBL
University Of Athens
Curated by ChEMBL
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Sun Pharma Advanced Research
Curated by ChEMBL
Sun Pharma Advanced Research
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 1.40nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of MMP12More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataIC50: 1.40nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of MMP10More data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMpH: 7.5 T: 2°CAssay Description:The compounds were tested for enzyme inhibition using fluorescence resonance energy transfer (FRET) assay. Fluorescence measurements were performed i...More data for this Ligand-Target Pair