BDBM268225 US10772893, Example 258::US11529356, Example 258::US9549932, 258

SMILES C[C@@H]1COCCN1c1cc(-c2c(C)nn(C)c2C)c2ccnc(-c3ccn[nH]3)c2n1

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 268225   

TargetSerine/threonine-protein kinase ATR(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM268225(US10772893, Example 258 | US11529356, Example 258 ...)
Affinity DataIC50:  7.66nMpH: 7.0Assay Description:To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM268225(US10772893, Example 258 | US11529356, Example 258 ...)
Affinity DataIC50:  7.66nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetATR-interacting protein/Serine/threonine-protein kinase ATR(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM268225(US10772893, Example 258 | US11529356, Example 258 ...)
Affinity DataIC50:  7.66nMAssay Description:To determine of binding activity of the test compounds, full-length human ATR protein was expressed and purified together with ATRIP as described abo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent