BDBM268486 4-[3-(2,6-dichloro-4-methoxy- benzoyl)-5,6,7,8- tetrahydroimidazo[1,5-a]pyridin- 1-yl]benzoic acid::US9550771, Example 85

SMILES COc1cc(Cl)c(C(=O)c2nc(c3CCCCn23)-c2ccc(cc2)C(O)=O)c(Cl)c1

InChI Key InChIKey=PONJXPVZFSRVPR-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 268486   

TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM268486(4-[3-(2,6-dichloro-4-methoxy- benzoyl)-5,6,7,8- te...)
Affinity DataEC50:  2.00E+3nMT: 2°CAssay Description:ssays were carried out in 16-μL reaction volumes in black 384 Plus F Proxiplates (Perkin-Elmer 6008269). All assay components except test ligand...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent