BDBM269380 (E)-ethyl 3-(4-((6- hydroxy-2-(4- hydroxyphenyl)benzo[b] thiophen-3-yl)oxy)-2- methylphenyl)acrylate::US10058534, 34

SMILES CCOC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)cc2)cc1C

InChI Key InChIKey=JDHAVQUAMURXAI-NTUHNPAUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269380   

TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269380((E)-ethyl 3-(4-((6- hydroxy-2-(4- hydroxyphenyl)be...)
Affinity DataIC50:  112nMpH: 7.4 T: 2°CAssay Description:Plate MCF7 cells at 0.3 million cells/mL (100 l/well) in black, clear-bottom 96-well plates (Greiner, catalog number 655090) in DMEM/F12 media (Gibco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269380((E)-ethyl 3-(4-((6- hydroxy-2-(4- hydroxyphenyl)be...)
Affinity DataIC50:  48nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent