BDBM269465 (E)-4-(4-((2-(4-fluoro- 2- (trifluoromethyl) phenyl)-6- hydroxybenzo[b]thiophen- 3-yl)oxy)phenyl)but- 3-en-2-one::US10058534, 120

SMILES CC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(F)cc2C(F)(F)F)cc1

InChI Key InChIKey=VBFMGQKUUDHWKQ-NSCUHMNNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 269465   

TargetEstrogen receptor(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM269465((E)-4-(4-((2-(4-fluoro- 2- (trifluoromethyl) pheny...)
Affinity DataIC50:  5.10nMpH: 5.1 T: 2°CAssay Description:The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent