BDBM269586 N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridinyl)-4H-1,2,4-triazol-3-yl)-2-propanesulfonamide::US10058550, Example 100.0::US10221162, Example 100.0::US9845310, Example 100.0

SMILES COc1cccc(n1)-c1nnc(NS(=O)(=O)C(C)C)n1-c1c(OC)cccc1OC

InChI Key InChIKey=KKMPLVKHWNCAOI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 269586   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269586(N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridiny...)
Affinity DataEC50:  110nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269586(N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridiny...)
Affinity DataEC50:  110nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269586(N-(4-(2,6-dimethoxyphenyl)-5-(6-methoxy-2-pyridiny...)
Affinity DataEC50:  110nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent