BDBM269595 (1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)-4H-1,2,4-triazol-3-yl)-1-ethoxy-1-(5-methyl-2-pyrimidinyl)-2-propanesulfonamide::US10058550, Example 109.0::US10221162, Example 109.0::US9845310, Example 109.0

SMILES CCO[C@@H]([C@H](C)S(=O)(=O)Nc1nnc(-c2cccnc2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1

InChI Key InChIKey=FZOYMOQCCXMSMQ-JTSKRJEESA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 269595   

TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269595((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)...)
Affinity DataEC50:  0.850nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV¿-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269595((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)...)
Affinity DataEC50:  0.850nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV-3 expression vector (Sig...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetApelin receptor(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM269595((1R,2S)-N-(4-(2,6-dimethoxyphenyl)-5-(3-pyridinyl)...)
Affinity DataEC50:  0.850nMAssay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV™-3 expression vector (Si...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent