BDBM26986 CHEMBL363707::HCO3-::SODIUM BICARBONATE::bicarbonate ion::hydrogen carbonate

SMILES: OC([O-])=O

InChI Key: InChIKey=BVKZGUZCCUSVTD-UHFFFAOYSA-M

Data: 80 KI

PDB links: 232 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 80 hits for monomerid = 26986   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	4.40E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory constant against carbonic anhydrase IV				Bioorg Med Chem Lett 14: 4563-7 (2004) Article DOI: 10.1016/j.bmcl.2004.06.073 BindingDB Entry DOI: 10.7270/Q2H995ZD
					More data for this Ligand-Target Pair
Carbonic Anhydrase XIII (Mus musculus (mouse))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.40E+8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10				Bioorg Med Chem Lett 14: 5435-9 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.07.086 BindingDB Entry DOI: 10.7270/Q2SN09QF
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli				Bioorg Med Chem Lett 14: 5435-9 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.07.086 BindingDB Entry DOI: 10.7270/Q2SN09QF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli				Bioorg Med Chem Lett 14: 5435-9 (2004) Checked by Author Article DOI: 10.1016/j.bmcl.2004.07.086 BindingDB Entry DOI: 10.7270/Q2SN09QF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA II				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	6.60E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA I				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	7.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA II				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA IX				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA I				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV				Bioorg Med Chem Lett 14: 5769-73 (2004) Article DOI: 10.1016/j.bmcl.2004.09.063 BindingDB Entry DOI: 10.7270/Q24X58JJ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant CA7				Bioorg Med Chem Lett 16: 3139-43 (2006) Article DOI: 10.1016/j.bmcl.2006.03.078 BindingDB Entry DOI: 10.7270/Q29W0G8R
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant CA7				Bioorg Med Chem Lett 16: 3139-43 (2006) Article DOI: 10.1016/j.bmcl.2006.03.078 BindingDB Entry DOI: 10.7270/Q29W0G8R
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biostrutture e Bioimmagini Curated by ChEMBL					Assay Description Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 23: 1626-30 (2013) Article DOI: 10.1016/j.bmcl.2013.01.087 BindingDB Entry DOI: 10.7270/Q23X8806
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 23: 1636-8 (2013) Article DOI: 10.1016/j.bmcl.2013.01.084 BindingDB Entry DOI: 10.7270/Q2VD70TX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 23: 1636-8 (2013) Article DOI: 10.1016/j.bmcl.2013.01.084 BindingDB Entry DOI: 10.7270/Q2VD70TX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Biochimica delle Proteine (IBP) Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem 21: 1465-9 (2013) Article DOI: 10.1016/j.bmc.2012.09.047 BindingDB Entry DOI: 10.7270/Q20R9QQQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kochi Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration method				Bioorg Med Chem Lett 23: 256-60 (2012) Article DOI: 10.1016/j.bmcl.2012.10.103 BindingDB Entry DOI: 10.7270/Q2ZC846G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kochi Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration method				Bioorg Med Chem Lett 23: 256-60 (2012) Article DOI: 10.1016/j.bmcl.2012.10.103 BindingDB Entry DOI: 10.7270/Q2ZC846G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 22: 7142-5 (2012) Article DOI: 10.1016/j.bmcl.2012.09.065 BindingDB Entry DOI: 10.7270/Q2930VB8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay				Bioorg Med Chem Lett 22: 7142-5 (2012) Article DOI: 10.1016/j.bmcl.2012.09.065 BindingDB Entry DOI: 10.7270/Q2930VB8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-carbonic anhydrase (Methanosarcina thermophila)	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	6.70E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory constant against Zn-Cam (Methanosarcina thermophila)				Bioorg Med Chem Lett 14: 4563-7 (2004) Article DOI: 10.1016/j.bmcl.2004.06.073 BindingDB Entry DOI: 10.7270/Q2H995ZD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-carbonic anhydrase (Methanosarcina thermophila)	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Firenze Curated by ChEMBL					Assay Description Inhibitory constant against Zn-Cam (Methanosarcina thermophila)				Bioorg Med Chem Lett 14: 4563-7 (2004) Article DOI: 10.1016/j.bmcl.2004.06.073 BindingDB Entry DOI: 10.7270/Q2H995ZD
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ degliStudi di Firenze Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method				Bioorg Med Chem 25: 575-580 (2017) Article DOI: 10.1016/j.bmc.2016.11.021 BindingDB Entry DOI: 10.7270/Q2M047FF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Gamma-carbonic anhydrase (Methanosarcina thermophila)	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	4.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Italy; Universit£ degliStudi di Firenze Curated by ChEMBL					Assay Description Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin...				Bioorg Med Chem 25: 575-580 (2017) Article DOI: 10.1016/j.bmc.2016.11.021 BindingDB Entry DOI: 10.7270/Q2M047FF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto di Bioscienze e Biorisorse, CNR Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as inhibition of CO2 hydration incubated for 15 mins prior to testing by stopped flow C...				Bioorg Med Chem 25: 2010-2015 (2017) Article DOI: 10.1016/j.bmc.2017.02.032 BindingDB Entry DOI: 10.7270/Q2JD5012
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CNR Curated by ChEMBL					Assay Description Inhibition of human CA2 incubated for 15 mins by stopped-flow CO2 hydration assay				Bioorg Med Chem 25: 4800-4804 (2017) BindingDB Entry DOI: 10.7270/Q2028V0P
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kochi Medical School Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase 2 by stopped-flow CO2 hydrase assay				Bioorg Med Chem Lett 24: 1127-32 (2014) BindingDB Entry DOI: 10.7270/Q2FX7DDZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB	1.20E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase-1 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4SV8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrases; II & IX (Homo sapiens (Human))	BDBM26986 (CHEMBL363707 | HCO3- | SODIUM BICARBONATE | bicarb...) Show SMILES OC([O-])=O Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB	8.50E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human carbonic anhydrase-2 at 20 degC preincubated for 15 mins by stopped-flow CO2 hydrase assay				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4SV8
					More data for this Ligand-Target Pair				3D Structure (crystal)