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BDBM26987 CHEMBL180485::CO3(2-)::SODIUM CARBONATE::carbonate::carbonate ion

SMILES: [O-]C([O-])=O

InChI Key: InChIKey=BVKZGUZCCUSVTD-UHFFFAOYSA-L

Data: 43 KI

PDB links: 305 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 43 hits for monomerid = 26987   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Alpha carbonic anhydrase


(Stylophora pistillata)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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PubMed
1.00E+4n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of Stylophora pistillata carbonic anhydrase by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic Anhydrase XV


(Mus musculus (mouse))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.06E+5n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Stylophora pistillata)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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PubMed
2.40E+5n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of Stylophora pistillata carbonic anhydrase 2 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
β-Carbonic anhydrase (βCA)


(Helicobacter pylori)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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4.20E+5n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...


Citation and Details
More data for this
Ligand-Target Pair
Alpha-carbonic anhydrase


(Helicobacter pylori (strain G27))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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6.60E+5 -4.26n/an/an/an/an/a7.520



Universit£ degli Studi di Firenze



Assay Description
Inhibition of Vibrio cholerae alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay


Citation and Details
More data for this
Ligand-Target Pair
α-Carbonic anhydrase (αCA)


(Helicobacter pylori)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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6.60E+5n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity Khalifah RG. The carbon dioxide hy...


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase 6 (CA-VI)


(Homo sapiens (Human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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PubMed
6.90E+5n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA6 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
Alpha-carbonic anhydrase


(Vibrio cholerae)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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4.64E+6 -3.13n/an/an/an/an/a7.520



Universit£ degli Studi di Firenze



Assay Description
Inhibition of Flaveria bidentis carbonic anhydrase 1 preincubated for 15 mins by stopped-flow CO2 hydrase assay


Citation and Details
More data for this
Ligand-Target Pair
Carbonic Anhydrase XIII


(Mus musculus (mouse))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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5.50E+6n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory activity against mouse carbonic anhydrase XIII expressed in Escherichia coli TOP 10


Bioorg Med Chem Lett 14: 5435-9 (2004)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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5.70E+6n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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5.70E+6n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA IV


Bioorg Med Chem Lett 14: 5763-7 (2004)

More data for this
Ligand-Target Pair
Beta-carbonic anhydrase


(Vibrio cholerae)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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6.70E+6 -2.91n/an/an/an/an/a7.520



Universit£ degli Studi di Firenze



Assay Description
Inhibition of Vibrio cholerae carbonic anhydrase beta preincubated for 15 mins by stopped-flow CO2 hydrase assay


Citation and Details
More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Methanosarcina thermophila)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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6.70E+6n/an/an/an/an/an/an/an/a



Istituto di Biochimica delle Proteine - CNR

Curated by ChEMBL


Assay Description
Inhibition of Methanosarcina thermophila recombinant gamma-CA by CO2 hydration assay


Bioorg Med Chem Lett 23: 4067-71 (2013)

More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Methanosarcina thermophila)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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6.70E+6n/an/an/an/an/an/an/an/a



Italy; Universit£ degliStudi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of Methanosarcina thermophila recombinant carbonic anhydrase gamma assessed as inhibition of CO2 hydration preincubated for 15 mins by Lin...


Citation and Details
More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Methanosarcina thermophila)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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6.70E+6n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse, CNR, Via Pietro Castellino 81, Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of archaeon Methanosarcina thermophila gamma-CA after 15 mins by stopped-flow/Co2 hydration assay


Bioorg Med Chem 23: 4405-9 (2015)

More data for this
Ligand-Target Pair
Gamma-carbonic anhydrase


(Vibrio cholerae)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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PubMed
8.20E+6 -2.80n/an/an/an/an/a7.520



Universit£ degli Studi di Firenze



Assay Description
Inhibition of Vibrio cholerae recombinant carbonic anhydrase gamma expressed in Escherichia coli DE3 cells preincubated for 15 mins by stopped-flow C...


Citation and Details
More data for this
Ligand-Target Pair
Astrosclerin-3


(Astrosclera willeyana)
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.35E+7n/an/an/an/an/an/an/an/a



Slovak Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of Astrosclera willeyana recombinant GST-tagged astrosclerin 3 expressed in Escherichia coli BL21-DE3-RIPL cells preincubated for 15 mins ...


Bioorg Med Chem Lett 22: 1314-6 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse (IBBR)-CNR, via P. Castellino 111, 80131 Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration method


Bioorg Med Chem Lett 24: 4389-96 (2014)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA I


Bioorg Med Chem Lett 14: 5763-7 (2004)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7 -2.44n/an/an/an/an/a7.520



Universit£ degli Studi di Firenze



Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped-flow CO2 hydrase assay


Citation and Details
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7 -2.44n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human cytosolic carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 22: 7142-5 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Kochi Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant wild type CA1 by stopped-flow CO2 hydration method


Bioorg Med Chem Lett 23: 256-60 (2012)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 23: 1636-8 (2013)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory activity against human carbonic anhydrase I expressed in Escherichia coli


Bioorg Med Chem Lett 14: 5435-9 (2004)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assay at pH 8.3


Bioorg Med Chem Lett 21: 3591-5 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 1 after 15 mins by CO2 hydrase assay at pH 7.5


Bioorg Med Chem 19: 1847-51 (2011)

More data for this
Ligand-Target Pair
Carbonic anhydrase


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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1.50E+7n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA1 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Kochi Medical School

Curated by ChEMBL


Assay Description
Inhibition of human recombinant wild type CA2 by stopped-flow CO2 hydration method


Bioorg Med Chem Lett 23: 256-60 (2012)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



UniversitÓ degli Studi di Firenze, Laboratorio di Chimica Bioinorganica, Rm. 188, Via della Lastruccia 3, I-50019 Sesto Fiorentino (Firenze), Italy.

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method


Bioorg Med Chem Lett 24: 4402-6 (2014)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7 -1.52n/an/an/an/an/a7.520



Universit£ degli Studi di Firenze



Assay Description
Inhibition of Helicobacter pylori alpha carbonic anhydrase preincubated for 15 mins by stopped-flow CO2 hydrase assay


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Italy; Universit£ degliStudi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carbonic anhydrase 2 assessed as inhibition of CO2 hydration preincubated for 15 mins by Lineweaver-burk plot method


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibitory activity against human carbonic anhydrase II expressed in Escherichia coli


Bioorg Med Chem Lett 14: 5435-9 (2004)

Checked by Author
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7 -1.52n/an/an/an/an/a7.520



Universita degli Studi di Firenze



Assay Description
An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...


Bioorg Med Chem Lett 19: 1155-8 (2009)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Istituto di Biostrutture e Bioimmagini

Curated by ChEMBL


Assay Description
Inhibition of human cytosolic carbonic anhydrase-2 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 23: 1626-30 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 after 15 mins by CO2 hydrase assay at pH 7.5


Bioorg Med Chem 19: 1847-51 (2011)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 23: 1636-8 (2013)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Università degli Studi di Milano

Curated by ChEMBL


Assay Description
Inhibition constant of anion against human carbonic anhydrase isozyme hCA II


Bioorg Med Chem Lett 14: 5763-7 (2004)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse, CNR, Via Pietro Castellino 81, Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of human CA2 after 15 mins by stopped-flow/Co2 hydration assay


Bioorg Med Chem 23: 4405-9 (2015)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Istituto di Bioscienze e Biorisorse (IBBR)-CNR, via P. Castellino 111, 80131 Napoli, Italy.

Curated by ChEMBL


Assay Description
Inhibition of human carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration method


Bioorg Med Chem Lett 24: 4389-96 (2014)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Centre Scientifique de Monaco

Curated by ChEMBL


Assay Description
Inhibition of human recombinant CA2 by stopped-flow CO2 hydration assay


Bioorg Med Chem Lett 21: 710-4 (2011)

Checked by Author
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of human cytosolic carbonic anhydrase 2 preincubated for 15 mins by stopped flow CO2 hydration assay


Bioorg Med Chem Lett 22: 7142-5 (2012)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Carbonic anhydrase 2


(Homo sapiens (human))
BDBM26987
PNG
(CHEMBL180485 | CO3(2-) | SODIUM CARBONATE | carbon...)
Show SMILES [O-]C([O-])=O
Show InChI InChI=1S/CH2O3/c2-1(3)4/h(H2,2,3,4)/p-2
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7.30E+7n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Firenze

Curated by ChEMBL


Assay Description
Inhibition of recombinant human carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assay at pH 8.3


Bioorg Med Chem Lett 21: 3591-5 (2011)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)