BDBM27007 2-[(3S,14S,17S,18R,20S)-19,19-dimethyl-3-{[(1-methylcyclohexyl)carbamoyl]amino}-2,16-dioxo-1,15-diazatricyclo[15.4.0.0^{18,20}]henicosan-14-yl]-2-oxoacetamide::ketoamide derived macrocyclic inhibitor, 31

SMILES CC1(C)[C@H]2CN3[C@@H]([C@@H]12)C(=O)N[C@@H](CCCCCCCCCC[C@H](NC(=O)NC1(C)CCCCC1)C3=O)C(=O)C(N)=O

InChI Key InChIKey=HOSMWPIMMSIMTO-LSBAASHUSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27007   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
Schering-Plough Research Institute

LigandPNGBDBM27007(2-[(3S,14S,17S,18R,20S)-19,19-dimethyl-3-{[(1-meth...)
Affinity DataKi:  36nM ΔG°:  -10.3kcal/molepH: 6.5 T: 2°CAssay Description:Proteolytic cleavage of the ester linkage between the Nva (L-norvaline) and the chromophore (PAP) was monitored for change in absorbance at 370 nm. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed