BDBM270284 (S)-3-(3-((6-(2,5-bis(trifluoromethyl)benzyl)-6-azaspiro[3.4]octan-2-yl)oxy)phenyl)-3-cyclopropylpropanoic acid::US10059667, Example 5B
SMILES OC(=O)C[C@@H](C1CC1)c1cccc(O[C@H]2CC3(C2)CCN(Cc2cc(ccc2C(F)(F)F)C(F)(F)F)C3)c1
InChI Key InChIKey=BJUYOUIXZQXLJQ-XAWUTYGVSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 270284
Affinity DataEC50: 2.14E+3nMT: 2°CAssay Description:The assay was performed in 96-well format. HEK cells stably expressing human GPR40 were plated to be 60-80% confluent within 72 h. After 72 h, the pl...More data for this Ligand-Target Pair
Affinity DataEC50: 113nMpH: 7.4 T: 2°CAssay Description:FLIPR (Fluorimetric Imaging Plate Reader, Molecular Devices) assays were performed to measure agonist-induced calcium mobilization of the stable clon...More data for this Ligand-Target Pair