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BDBM270480 US10071086, Compound 24

SMILES: CN(C)Cc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cc(F)cc(c3)N3CCOCC3)c2c1

InChI Key: InChIKey=CNBQEDMYQHBLDI-SJCQXOIGSA-N

Data: 1 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270480   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (human))
BDBM270480
PNG
(US10071086, Compound 24)
Show SMILES CN(C)Cc1cncc(c1)-c1cnc2[nH]nc(-c3nc4c(cncc4[nH]3)-c3cc(F)cc(c3)N3CCOCC3)c2c1
Show InChI InChI=1S/C30H26FN9O/c1-39(2)17-18-7-20(13-32-12-18)21-10-24-28(37-38-29(24)34-14-21)30-35-26-16-33-15-25(27(26)36-30)19-8-22(31)11-23(9-19)40-3-5-41-6-4-40/h7-16H,3-6,17H2,1-2H3/b30-28+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 21n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair