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BDBM270606 US10071086, Compound 114

SMILES: Fc1cccc(c1)-c1cncc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CC2)c1

InChI Key: InChIKey=VYUWKTAEBZUVME-SHHOIMCASA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270606   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (human))
BDBM270606
PNG
(US10071086, Compound 114)
Show SMILES Fc1cccc(c1)-c1cncc2[nH]c(nc12)-c1n[nH]c2ncc(cc12)-c1cncc(NC(=O)C2CC2)c1
Show InChI InChI=1S/C27H17FN8O/c28-18-3-1-2-15(6-18)21-12-30-13-22-23(21)34-26(33-22)24-20-8-17(10-31-25(20)36-35-24)16-7-19(11-29-9-16)32-27(37)14-4-5-14/h1-3,6-14H,4-5H2,(H,32,37)/b26-24+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 11n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair