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BDBM270830 US10071086, Compound 325

SMILES: CC(C)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4ccncc4[nH]3)c2c1

InChI Key: InChIKey=BQWHPGUOTQCEKT-ZZEZOPTASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 270830   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenomatous polyposis coli protein


(Homo sapiens (human))
BDBM270830
PNG
(US10071086, Compound 325)
Show SMILES CC(C)Nc1cncc(c1)-c1cnc2[nH]nc(-c3nc4ccncc4[nH]3)c2c1
Show InChI InChI=1S/C20H16N8/c1-11(2)24-14-5-12(7-22-9-14)13-6-15-18(27-28-19(15)23-8-13)20-25-16-3-4-21-10-17(16)26-20/h3-11,24H,1-2H3/b20-18-
PDB

GoogleScholar
AffyNet 
UniChem
n/an/a 58n/an/an/an/an/an/a



Samumed, LLC

US Patent


Assay Description
Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...


US Patent US10071086 (2018)

More data for this
Ligand-Target Pair