BDBM270858 US10059709, 4

SMILES CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1ncnc2[nH]c(nc12)-c1ccccc1

InChI Key InChIKey=ROBRQYAFCIRVMR-KOMQPUFPSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 270858   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270858(US10059709, 4)
Affinity DataIC50: >1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270858(US10059709, 4)
Affinity DataIC50: >1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270858(US10059709, 4)
Affinity DataIC50: >1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent