BDBM270864 US10059709, 10

SMILES CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)N(C)c1cc(Cl)nc(N)n1

InChI Key InChIKey=YSFPFEAQYFWCQC-MGCOHNPYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 270864   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270864(US10059709, 10)
Affinity DataIC50: >1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270864(US10059709, 10)
Affinity DataIC50: >1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Elanco Tiergesundheit

US Patent
LigandPNGBDBM270864(US10059709, 10)
Affinity DataIC50: >1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent